An atypical DYRK kinase connects quorum-sensing with posttranscriptional gene regulation in Trypanosoma brucei

An atypical DYRK kinase connects quorum-sensing with posttranscriptional gene regulation in Trypanosoma brucei

The sleeping sickness parasite, Trypanosoma brucei, uses quorum sensing (QS) to balance proliferation and transmission potential in the mammal bloodstream. A signal transduction cascade regulates this process, a component of which is a divergent member of the DYRK family of protein kinases, TbDYRK....

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Bibliographic Details
Main Authors: Mathieu Cayla, Lindsay McDonald, Paula MacGregor, Keith Matthews
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-03-01
Series:eLife
Subjects:
parasite
Trypanosoma
differentiation
DYRK
protein kinase
gene expression
Online Access:https://elifesciences.org/articles/51620

Internet

https://elifesciences.org/articles/51620

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