An atypical DYRK kinase connects quorum-sensing with posttranscriptional gene regulation in Trypanosoma brucei

by Mathieu Cayla, Lindsay McDonald, Paula MacGregor, Keith Matthews
Published 2020-03-01

How Does the VSG Coat of Bloodstream Form African Trypanosomes Interact with External Proteins?

by Angela Schwede, Olivia J S Macleod, Paula MacGregor, Mark Carrington
Published 2015-12-01

A Receptor's Tale: An Eon in the Life of a Trypanosome Receptor.

by Matthew K Higgins, Harriet Lane-Serff, Paula MacGregor, Mark Carrington
Published 2017-01-01

Structural basis for ligand and innate immunity factor uptake by the trypanosome haptoglobin-haemoglobin receptor

by Harriet Lane-Serff, Paula MacGregor, Edward D Lowe, Mark Carrington, Matthew K Higgins
Published 2014-12-01

Mitochondrial DNA is critical for longevity and metabolism of transmission stage Trypanosoma brucei.

by Caroline E Dewar, Paula MacGregor, Sinclair Cooper, Matthew K Gould, Keith R Matthews, Nicholas J Savill, Achim Schnaufer
Published 2018-07-01

Evolutionary diversification of the trypanosome haptoglobin-haemoglobin receptor from an ancestral haemoglobin receptor

by Harriet Lane-Serff, Paula MacGregor, Lori Peacock, Olivia JS Macleod, Christopher Kay, Wendy Gibson, Matthew K Higgins, Mark Carrington
Published 2016-04-01

Non-linear hierarchy of the quorum sensing signalling pathway in bloodstream form African trypanosomes.

by Lindsay McDonald, Mathieu Cayla, Alasdair Ivens, Binny M Mony, Paula MacGregor, Eleanor Silvester, Kirsty McWilliam, Keith R Matthews
Published 2018-06-01

Targeting cattle-borne zoonoses and cattle pathogens using a novel trypanosomatid-based delivery system.

by G Adam Mott, Raymond Wilson, Anuruddika Fernando, Ailie Robinson, Paula MacGregor, David Kennedy, Dick Schaap, Jacqueline B Matthews, Keith R Matthews
Published 2011-10-01

A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies

by Olivia J. S. Macleod, Jean-Mathieu Bart, Paula MacGregor, Lori Peacock, Nicholas J. Savill, Svenja Hester, Sophie Ravel, Jack D. Sunter, Camilla Trevor, Steven Rust, Tristan J. Vaughan, Ralph Minter, Shabaz Mohammed, Wendy Gibson, Martin C. Taylor, Matthew K. Higgins, Mark Carrington
Published 2020-03-01

A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis.

by Paula MacGregor, Andrea L Gonzalez-Munoz, Fatoumatta Jobe, Martin C Taylor, Steven Rust, Alan M Sandercock, Olivia J S Macleod, Katrien Van Bocxlaer, Amanda F Francisco, Francois D'Hooge, Arnaud Tiberghien, Conor S Barry, Philip Howard, Matthew K Higgins, Tristan J Vaughan, Ralph Minter, Mark Carrington
Published 2019-05-01