Trypanosoma cruzi amastigotes that persist in the colon during chronic stage murine infections have a reduced replication rate

by Alexander I. Ward, Francisco Olmo, Richard L. Atherton, Martin C. Taylor, John M. Kelly
Published 2020-12-01

Highly Sensitive Bioluminescence Imaging Models for Chagas Disease Drug Discovery

by John M. Kelly, Amanda F. Francisco, Shiromani Jayawardhana, Martin C. Taylor, Michael D. Lewis
Published 2017-10-01

The Trypanosoma cruzi vitamin C dependent peroxidase confers protection against oxidative stress but is not a determinant of virulence.

by Martin C Taylor, Michael D Lewis, Amanda Fortes Francisco, Shane R Wilkinson, John M Kelly
Published 2015-04-01

Imaging the development of chronic Chagas disease after oral transmission

by Michael D. Lewis, Amanda F. Francisco, Shiromani Jayawardhana, Harry Langston, Martin C. Taylor, John M. Kelly
Published 2018-07-01

Intracellular DNA replication and differentiation of Trypanosoma cruzi is asynchronous within individual host cells in vivo at all stages of infection.

by Martin C Taylor, Alexander Ward, Francisco Olmo, Shiromani Jayawardhana, Amanda F Francisco, Michael D Lewis, John M Kelly
Published 2020-03-01

Challenges in Chagas Disease Drug Development

by Amanda F. Francisco, Shiromani Jayawardhana, Francisco Olmo, Michael D. Lewis, Shane R. Wilkinson, Martin C. Taylor, John M. Kelly
Published 2020-06-01

Synthesis, anti-bacterial and anti-protozoal activities of amidinobenzimidazole derivatives and their interactions with DNA and RNA

by Andrea Bistrović, Luka Krstulović, Ivana Stolić, Domagoj Drenjančević, Jasminka Talapko, Martin C. Taylor, John M. Kelly, Miroslav Bajić, Silvana Raić-Malić
Published 2018-01-01

Tetrasubstituted Imidazolium Salts as Potent Antiparasitic Agents against African and American Trypanosomiases

by Ouldouz Ghashghaei, Nicola Kielland, Marc Revés, Martin C. Taylor, John M. Kelly, Ornella Di Pietro, Diego Muñoz-Torrero, Belén Pérez, Rodolfo Lavilla
Published 2018-01-01

Synthesis, antiproliferative and antitrypanosomal activities, and DNA binding of novel 6-amidino-2-arylbenzothiazoles

by Livio Racané, Valentina Rep, Sandra Kraljević Pavelić, Petra Grbčić, Iva Zonjić, Marijana Radić Stojković, Martin C. Taylor, John M. Kelly, Silvana Raić-Malić
Published 2021-01-01

In Vivo Analysis of Trypanosoma cruzi Persistence Foci at Single-Cell Resolution

by Alexander I. Ward, Michael D. Lewis, Archie A. Khan, Conor J. McCann, Amanda F. Francisco, Shiromani Jayawardhana, Martin C. Taylor, John M. Kelly
Published 2020-08-01

Highly sensitive in vivo imaging of Trypanosoma brucei expressing "red-shifted" luciferase.

by Alex P McLatchie, Hollie Burrell-Saward, Elmarie Myburgh, Michael D Lewis, Theresa H Ward, Jeremy C Mottram, Simon L Croft, John M Kelly, Martin C Taylor
Published 2013-11-01

In vivo imaging of trypanosome-brain interactions and development of a rapid screening test for drugs against CNS stage trypanosomiasis.

by Elmarie Myburgh, Jonathan A Coles, Ryan Ritchie, Peter G E Kennedy, Alex P McLatchie, Jean Rodgers, Martin C Taylor, Michael P Barrett, James M Brewer, Jeremy C Mottram
Published 2013-01-01

Drug-cured experimental Trypanosoma cruzi infections confer long-lasting and cross-strain protection.

by Gurdip Singh Mann, Amanda F Francisco, Shiromani Jayawardhana, Martin C Taylor, Michael D Lewis, Francisco Olmo, Elisangela Oliveira de Freitas, Fabiana M S Leoratti, Cesar López-Camacho, Arturo Reyes-Sandoval, John M Kelly
Published 2020-04-01

A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies

by Olivia J. S. Macleod, Jean-Mathieu Bart, Paula MacGregor, Lori Peacock, Nicholas J. Savill, Svenja Hester, Sophie Ravel, Jack D. Sunter, Camilla Trevor, Steven Rust, Tristan J. Vaughan, Ralph Minter, Shabaz Mohammed, Wendy Gibson, Martin C. Taylor, Matthew K. Higgins, Mark Carrington
Published 2020-03-01

A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis.

by Paula MacGregor, Andrea L Gonzalez-Munoz, Fatoumatta Jobe, Martin C Taylor, Steven Rust, Alan M Sandercock, Olivia J S Macleod, Katrien Van Bocxlaer, Amanda F Francisco, Francois D'Hooge, Arnaud Tiberghien, Conor S Barry, Philip Howard, Matthew K Higgins, Tristan J Vaughan, Ralph Minter, Mark Carrington
Published 2019-05-01