On the effect of phylogenetic correlations in coevolution-based contact prediction in proteins.

Coevolution-based contact prediction, either directly by coevolutionary couplings resulting from global statistical sequence models or using structural supervision and deep learning, has found widespread application in protein-structure prediction from sequence. However, one of the basic assumptions...

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Bibliographic Details
Main Authors: Edwin Rodriguez Horta, Martin Weigt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-05-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1008957