Critical Role of Zur and SmtB in Zinc Homeostasis of Mycobacterium smegmatis

Critical Role of Zur and SmtB in Zinc Homeostasis of Mycobacterium smegmatis

Zinc is crucial for many biological processes, as it is an essential cofactor of enzymes and a structural component of regulatory and DNA binding proteins. Hence, all living cells require zinc to maintain constant intracellular levels. However, in excess, zinc is toxic. Therefore, cellular zinc home...

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Bibliographic Details
Main Authors: Elke Goethe, Kristin Laarmann, Janita Lührs, Michael Jarek, Jochen Meens, Astrid Lewin, Ralph Goethe
Format: Article
Language:English
Published: American Society for Microbiology 2020-04-01
Series:mSystems
Subjects:
zinc homeostasis
zinc transporter
zinc starvation
zinc excess
zur regulon
smtb regulon
zinc regulation
zita
zinc import
zinc export
transcriptomics
mycobacteria
znuabc
alternative ribosomal proteins
chromatin immunoprecipitation
coregulation
export
import
Online Access:https://doi.org/10.1128/mSystems.00880-19

Internet

https://doi.org/10.1128/mSystems.00880-19

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