GSTT1 and GSTM1 null variants in Mestizo and Amerindian populations from northwestern Mexico and a literature review

GSTT1 and GSTM1 null variants in Mestizo and Amerindian populations from northwestern Mexico and a literature review

Abstract The GSTT1 and GSTM1 genes are key molecules in cellular detoxification. Null variants in these genes are associated with increase susceptibility to developing different types of cancers. The aim of this study was to determine the prevalence of GSTT1 and GSTM1 null genotypes in Mestizo and A...

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Bibliographic Details
Main Authors: Luz Elena Palma-Cano, Emilio J. Córdova, Lorena Orozco, Angélica Martínez-Hernández, Miguel Cid, Irene Leal-Berumen, Angel Licón-Trillo, Ruth Lechuga-Valles, Mauricio González-Ponce, Everardo González-Rodríguez, Verónica Moreno-Brito
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2017-11-01
Series:Genetics and Molecular Biology
Subjects:
Oxidative stress
GSTT1
GSTM1
null variants
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572017005027102&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572017005027102&lng=en&tlng=en

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