Optimization of secretion and surface localization of heterologous OVA protein in mycobacteria by using LipY as a carrier
Abstract Background Mycobacterium bovis Bacille Calmette-Guérin (BCG) is not only used as a vaccine against tuberculosis but also protects against leprosy and is used as part of bladder cancer treatment to induce a protective immune response. However, protection by BCG vaccination is not optimal. To...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-03-01
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Series: | Microbial Cell Factories |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12934-019-1093-1 |