Experimental validation of the RATE tool for inferring HLA restrictions of T cell epitopes

Experimental validation of the RATE tool for inferring HLA restrictions of T cell epitopes

Abstract Background The RATE tool was recently developed to computationally infer the HLA restriction of given epitopes from immune response data of HLA typed subjects without additional cumbersome experimentation. Results Here, RATE was validated using experimentally defined restriction data from a...

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Bibliographic Details
Main Authors: Sinu Paul, Cecilia S. Lindestam Arlehamn, Veronique Schulten, Luise Westernberg, John Sidney, Bjoern Peters, Alessandro Sette
Format: Article
Language:English
Published: BMC 2017-06-01
Series:BMC Immunology
Subjects:
HLA restriction
HLA association
MHC
Epitope
T cell
RATE
Online Access:http://link.springer.com/article/10.1186/s12865-017-0204-1

Internet

http://link.springer.com/article/10.1186/s12865-017-0204-1

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