The structural basis for dynamic DNA binding and bridging interactions which condense the bacterial centromere

The structural basis for dynamic DNA binding and bridging interactions which condense the bacterial centromere

The ParB protein forms DNA bridging interactions around parS to condense DNA and earmark the bacterial chromosome for segregation. The molecular mechanism underlying the formation of these ParB networks is unclear. We show here that while the central DNA binding domain is essential for anchoring at...

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Bibliographic Details
Main Authors: Gemma LM Fisher, César L Pastrana, Victoria A Higman, Alan Koh, James A Taylor, Annika Butterer, Timothy Craggs, Frank Sobott, Heath Murray, Matthew P Crump, Fernando Moreno-Herrero, Mark S Dillingham
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-12-01
Series:eLife
Subjects:
chromosome segregation
bacterial centromere
Spo0J
single-molecule
NMR
Online Access:https://elifesciences.org/articles/28086

Internet

https://elifesciences.org/articles/28086

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