TET-mediated epimutagenesis of the Arabidopsis thaliana methylome

In plants, variation in DNA methylation can influence agronomically important traits. Here the authors show that expression of a human Ten-eleven translocation enzyme can generate heritable hypomethylation alleles in Arabidopsis, providing a novel method to manipulate DNA methylation for breeding an...

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Bibliographic Details
Main Authors: Lexiang Ji, William T. Jordan, Xiuling Shi, Lulu Hu, Chuan He, Robert J. Schmitz
Format: Article
Language:English
Published: Nature Publishing Group 2018-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-03289-7