Measles Virus-Based Treatments Trigger a Pro-inflammatory Cascade and a Distinctive Immunopeptidome in Glioblastoma

Measles Virus-Based Treatments Trigger a Pro-inflammatory Cascade and a Distinctive Immunopeptidome in Glioblastoma

Glioblastoma is an aggressive primary brain tumor with bad prognosis. On the other hand, oncolytic measles virus (MeV) therapy is an experimental glioma treatment strategy with clinical safety and first evidence of anti-tumoral efficacy. Therefore, we investigated the combination of MeV with convent...

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Bibliographic Details
Main Authors: Srinath Rajaraman, Denis Canjuga, Michael Ghosh, Marius Cosmin Codrea, Raika Sieger, Florian Wedekink, Marcos Tatagiba, Marilin Koch, Ulrich M. Lauer, Sven Nahnsen, Hans-Georg Rammensee, Michael D. Mühlebach, Stefan Stevanovic, Ghazaleh Tabatabai
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Molecular Therapy: Oncolytics
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770518300470

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http://www.sciencedirect.com/science/article/pii/S2372770518300470

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