Netazepide Inhibits Expression of Pappalysin 2 in Type 1 Gastric Neuroendocrine TumorsSummary

Netazepide Inhibits Expression of Pappalysin 2 in Type 1 Gastric Neuroendocrine TumorsSummary

Background & Aims: In patients with autoimmune atrophic gastritis and achlorhydria, hypergastrinemia is associated with the development of type 1 gastric neuroendocrine tumors (gNETs). Twelve months of treatment with netazepide (YF476), an antagonist of the cholecystokinin B receptor (CCKBR...

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Bibliographic Details
Main Authors: Katie A. Lloyd, Bryony N. Parsons, Michael D. Burkitt, Andrew R. Moore, Stamatia Papoutsopoulou, Malcolm Boyce, Carrie A. Duckworth, Klaire Exarchou, Nathan Howes, Lucille Rainbow, Yongxiang Fang, Claus Oxvig, Steven Dodd, Andrea Varro, Neil Hall, D. Mark Pritchard
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Tumorigenesis
Carcinogenesis
Mouse Model
Hormone
Signal Transduction
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X20300175

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http://www.sciencedirect.com/science/article/pii/S2352345X20300175

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