Epigenomic analysis of 5-hydroxymethylcytosine (5hmC) reveals novel DNA methylation markers for lung cancers

Background: DNA methylation at the fifth position of cytosine (5mC) is a common epigenetic alteration affecting a range of cellular processes. In recent years, 5-hydroxymethylcytosine (5hmC), an oxidized form of 5mC, has risen broad interests as a potential biomarker for lung cancer diagnosis and su...

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Bibliographic Details
Main Authors: Zhihui Wang, Mulong Du, Qianyu Yuan, Yichen Guo, John N. Hutchinson, Li Su, Yinan Zheng, Jun Wang, Lorelei A. Mucci, Xihong Lin, Lifang Hou, David C. Christiani
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558619303033