A Proteomic Atlas of Lineage and Cancer-Polarized Expression Modules in Myeloid Cells Modeling Immunosuppressive Tumor-Infiltrating Subsets

Monocytic and granulocytic myeloid-derived suppressor cells together with tumor-infiltrating macrophages constitute the main tumor-infiltrating immunosuppressive myeloid populations. Due to the phenotypic resemblance to conventional myeloid cells, their identification and purification from within th...

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Main Authors: Ester Blanco, Maria Ibañez-Vea, Carlos Hernandez, Lylia Drici, Xabier Martínez de Morentin, Maria Gato, Karina Ausin, Ana Bocanegra, Miren Zuazo, Luisa Chocarro, Hugo Arasanz, Gonzalo Fernandez-Hinojal, Joaquin Fernandez-Irigoyen, Cristian Smerdou, Maider Garnica, Miriam Echaide, Leticia Fernandez, Pilar Morente, Pablo Ramos-Castellanos, Diana Llopiz, Enrique Santamaria, Martin R. Larsen, David Escors, Grazyna Kochan
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Journal of Personalized Medicine
Subjects:
Online Access:https://www.mdpi.com/2075-4426/11/6/542