MTSS1 is epigenetically regulated in glioma cells and inhibits glioma cell motility

Epigenetic silencing by DNA methylation in brain tumors has been reported for many genes, however, their function on pathogenesis needs to be evaluated. We investigated the MTSS1 gene, identified as hypermethylated by differential methylation hybridization (DMH). Fifty-nine glioma tissue samples and...

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Bibliographic Details
Main Authors: Daniel Luxen, Gerrit H. Gielen, Anke Waha, Lukas Isselstein, Tim Müller, Philipp Koch, Jennifer Hammes, Albert Becker, Matthias Simon, Peter Wurst, Elmar Endl, Torsten Pietsch, Marco Gessi, Andreas Waha
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523316301334