Sortilin, SorCS1b, and SorLA Vps10p sorting receptors, are novel γ-secretase substrates
<p>Abstract</p> <p>Background</p> <p>The mammalian Vps10p sorting receptor family is a group of 5 type I membrane homologs (Sortilin, SorLA, and SorCS1-3). These receptors bind various cargo proteins via their luminal Vps10p domains and have been shown to mediate a vari...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2006-06-01
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Series: | Molecular Neurodegeneration |
Online Access: | http://www.molecularneurodegeneration.com/content/1/1/3 |