Altered Hippocampal Epigenetic Regulation Underlying Reduced Cognitive Development in Response to Early Life Environmental Insults

Altered Hippocampal Epigenetic Regulation Underlying Reduced Cognitive Development in Response to Early Life Environmental Insults

The hippocampus is involved in learning and memory and undergoes significant growth and maturation during the neonatal period. Environmental insults during this developmental timeframe can have lasting effects on brain structure and function. This study assessed hippocampal DNA methylation and gene...

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Bibliographic Details
Main Authors: Kyle M. Schachtschneider, Michael E. Welge, Loretta S. Auvil, Sulalita Chaki, Laurie A. Rund, Ole Madsen, Monica R.P. Elmore, Rodney W. Johnson, Martien A.M. Groenen, Lawrence B. Schook
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Genes
Subjects:
porcine biomedical models
hippocampus
cognitive development
dna methylation
rna-seq
machine learning
Online Access:https://www.mdpi.com/2073-4425/11/2/162

Internet

https://www.mdpi.com/2073-4425/11/2/162

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