Innate activation of human primary epithelial cells broadens the host response to Mycobacterium tuberculosis in the airways.

Innate activation of human primary epithelial cells broadens the host response to Mycobacterium tuberculosis in the airways.

Early events in the human airways determining whether exposure to Mycobacterium tuberculosis (Mtb) results in acquisition of infection are poorly understood. Epithelial cells are the dominant cell type in the lungs, but little is known about their role in tuberculosis. We hypothesised that human pri...

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Bibliographic Details
Main Authors: Ann-Kathrin Reuschl, Michael R Edwards, Robert Parker, David W Connell, Long Hoang, Alice Halliday, Hannah Jarvis, Nazneen Siddiqui, Corrina Wright, Samuel Bremang, Sandra M Newton, Peter Beverley, Robin J Shattock, Onn Min Kon, Ajit Lalvani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-09-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1006577

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https://doi.org/10.1371/journal.ppat.1006577

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