Dynamics of HIV latency and reactivation in a primary CD4+ T cell model.

Dynamics of HIV latency and reactivation in a primary CD4+ T cell model.

HIV latency is a major obstacle to curing infection. Current strategies to eradicate HIV aim at increasing transcription of the latent provirus. In the present study we observed that latently infected CD4+ T cells from HIV-infected individuals failed to produce viral particles upon ex vivo exposure...

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Bibliographic Details
Main Authors: Pejman Mohammadi, Julia di Iulio, Miguel Muñoz, Raquel Martinez, István Bartha, Matthias Cavassini, Christian Thorball, Jacques Fellay, Niko Beerenwinkel, Angela Ciuffi, Amalio Telenti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4038609?pdf=render

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http://europepmc.org/articles/PMC4038609?pdf=render

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