Investigation of the acetylation mechanism by GCN5 histone acetyltransferase.

The histone acetylation of post-translational modification can be highly dynamic and play a crucial role in regulating cellular proliferation, survival, differentiation and motility. Of the enzymes that mediate post-translation modifications, the GCN5 of the histone acetyltransferase (HAT) proteins...

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Bibliographic Details
Main Authors: Junfeng Jiang, Junyan Lu, Dan Lu, Zhongjie Liang, Lianchun Li, Sisheng Ouyang, Xiangqian Kong, Hualiang Jiang, Bairong Shen, Cheng Luo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22574209/?tool=EBI