<i>Mycobacterium tuberculosis</i> H<sub>2</sub>S Functions as a Sink to Modulate Central Metabolism, Bioenergetics, and Drug Susceptibility

<i>Mycobacterium tuberculosis</i> H<sub>2</sub>S Functions as a Sink to Modulate Central Metabolism, Bioenergetics, and Drug Susceptibility

H<sub>2</sub>S is a potent gasotransmitter in eukaryotes and bacteria. Host-derived H<sub>2</sub>S has been shown to profoundly alter <i>M. tuberculosis</i> (<i>Mtb</i>) energy metabolism and growth. However, compelling evidence for endogenous producti...

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Bibliographic Details
Main Authors: Tafara T. R. Kunota, Md. Aejazur Rahman, Barry E. Truebody, Jared S. Mackenzie, Vikram Saini, Dirk A. Lamprecht, John H. Adamson, Ritesh R. Sevalkar, Jack R. Lancaster, Michael Berney, Joel N. Glasgow, Adrie J. C. Steyn
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Antioxidants
Subjects:
<i>Mycobacterium tuberculosis</i>
H<sub>2</sub>S
energy metabolism
bioenergetics
respiration
metabolomics
Online Access:https://www.mdpi.com/2076-3921/10/8/1285

Internet

https://www.mdpi.com/2076-3921/10/8/1285

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