Cytomegalovirus (CMV)-Specific Perforin and Granzyme B ELISPOT Assays Detect Reactivation of CMV Infection in Inflammatory Bowel Disease

Cytomegalovirus (CMV)-Specific Perforin and Granzyme B ELISPOT Assays Detect Reactivation of CMV Infection in Inflammatory Bowel Disease

The role of cytomegalovirus (CMV) infection in the pathogenesis and exacerbation of Inflammatory Bowel Disease (IBD) has been unresolved. Typically, the CMV genome remains dormant in infected cells, but a breakdown of immune surveillance can lead to re-activation of viral replication in the gut muco...

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Bibliographic Details
Main Authors: Paul V. Lehmann, Jan Heidemann, Matthias Ross, Dominik Bettenworth, Tobias M. Nowacki, Andreas Lügering
Format: Article
Language:English
Published: MDPI AG 2012-04-01
Series:Cells
Subjects:
cytomegalovirus infection
CMV
ELISPOT
immunomonitoring
inflammatory bowel disease
Online Access:http://www.mdpi.com/2073-4409/1/2/35

Internet

http://www.mdpi.com/2073-4409/1/2/35

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