Evaluation of Effect of As2O3 on Cell Growth, Cell Cycle and Apoptosis in Human Leukemia Cell Line HL-60
Introduction: Arsenic Trioxide (As2O3) causes antitumor effects by various mechanisms, including degradation of PML-RARA in the acute promyelocytic cells, growth inhibition and induction of apoptosis. However, the precise mechanisms of these processes remain incompletely understood. The purpose of t...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Tehran University of Medical Sciences
2012-01-01
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Series: | International Journal of Hematology-Oncology and Stem Cell Research |
Subjects: | |
Online Access: | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/20914.pdf&manuscript_id=20914 |
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