Cooperative nutrient accumulation sustains growth of mammalian cells

The coordination of metabolic processes to allow increased nutrient uptake and utilization for macromolecular synthesis is central for cell growth. Although studies of bulk cell populations have revealed important metabolic and signaling requirements that impact cell growth on long time scales, whet...

Full description

Bibliographic Details
Main Authors: Son, Sungmin (Contributor), Stevens, Mark M. (Contributor), Chao, Hui Xiao (Contributor), Weng, Yaochung (Contributor), Wood, Kris (Author), Vander Heiden, Matthew G. (Contributor), Hosios, Aaron Marc (Contributor), Schweitzer, Lawrence David (Contributor), Thoreen, Carson C (Author), Sabatini, David (Author), Manalis, Scott R (Author)
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor), Whitehead Institute for Biomedical Research (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Thoreen, Carson (Contributor), Sabatini, David M. (Contributor), Manalis, Scott R. (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2016-01-20T00:50:57Z.
Subjects:
Online Access:Get fulltext