Acyl-CoA Dehydrogenase Drives Heat Adaptation by Sequestering Fatty Acids

Cells adapt to temperature shifts by adjusting levels of lipid desaturation and membrane fluidity. This fundamental process occurs in nearly all forms of life, but its mechanism in eukaryotes is unknown. We discovered that the evolutionarily conserved C. elegans gene acdh-11 (acyl CoAdehydrogenase,...

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Bibliographic Details
Main Authors: Li, Zhijie (Author), Sun, Fang (Author), Chen, Sidi (Author), Rothe, Michael (Author), Menzel, Ralph (Author), Ma, Dengke (Contributor), Lu, Alice Y. (Contributor), Horvitz, Howard Robert (Contributor), Sun, Fei, S.B. Massachusetts Institute of Technology (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), McGovern Institute for Brain Research at MIT (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Elsevier, 2016-11-22T21:35:35Z.
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