CXCL13 is a plasma biomarker of germinal center activity

CXCL13 is a plasma biomarker of germinal center activity

Significantly higher levels of plasma CXCL13 [chemokine (C-X-C motif) ligand 13] were associated with the generation of broadly neutralizing antibodies (bnAbs) against HIV in a large longitudinal cohort of HIV-infected individuals. Germinal centers (GCs) perform the remarkable task of optimizing B-c...

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Main Authors: Havenar-Daughton, Colin (Author), Lindqvist, Madelene (Contributor), Heit, Antje (Author), Wu, Jennifer E. (Author), Reiss, Samantha M. (Author), Kendric, Kayla (Author), Bélanger, Simon (Author), Kasturi, Sudhir Pai (Author), Landais, Elise (Author), Akondy, Rama S. (Author), McGuire, Helen M. (Author), Bothwell, Marcella (Author), Vagefi, Parsia A. (Author), Scully, Eileen (Contributor), Tomaras, Georgia D. (Author), Davis, Mark M. (Author), Poignard, Pascal (Author), Ahmed, Rafi (Author), Walker, Bruce D. (Contributor), Pulendran, Bali (Author), McElrath, M. Juliana (Author), Kaufmann, Daniel E. (Contributor), Crotty, Shane (Author)
Other Authors: Ragon Institute of MGH, MIT and Harvard (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2017-02-14T21:58:07Z.
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