A Flow Cytometric Clonogenic Assay Reveals the Single-Cell Potency of Doxorubicin

A Flow Cytometric Clonogenic Assay Reveals the Single-Cell Potency of Doxorubicin

Standard cell proliferation assays use bulk media drug concentration to ascertain the potency of chemotherapeutic drugs; however, the relevant quantity is clearly the amount of drug actually taken up by the cell. To address this discrepancy, we have developed a flow cytometric clonogenic assay to co...

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Bibliographic Details
Main Authors: Kulkarni, Chethana (Author), Betts, Alison M. (Author), Maass, Katie F. (Contributor), Quadir, Mohiuddin Abdul (Contributor), Hammond, Paula T. (Contributor), Wittrup, Karl Dane (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Wiley Blackwell, 2017-02-21T17:05:29Z.
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