CDK7-Dependent Transcriptional Addiction in Triple-Negative Breast Cancer

CDK7-Dependent Transcriptional Addiction in Triple-Negative Breast Cancer

Triple-negative breast cancer (TNBC) is a highly aggressive form of breast cancer that exhibits extremely high levels of genetic complexity and yet a relatively uniform transcriptional program. We postulate that TNBC might be highly dependent on uninterrupted transcription of a key set of genes with...

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Bibliographic Details
Main Authors: Wang, Yubao (Author), Zhang, Tinghu (Author), Kwiatkowski, Nicholas (Author), Abraham, Brian J (Author), Lee, Tong Ihn (Author), Xie, Shaozhen (Author), Yuzugullu, Haluk (Author), Von, Thanh (Author), Li, Heyuan (Author), Lin, Ziao (Author), Stover, Daniel G (Author), Lim, Elgene (Author), Wang, Zhigang C (Author), Iglehart, J. Dirk (Author), Gray, Nathanael S (Author), Zhao, Jean J (Author), Young, Richard A. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Young, Richard A (Contributor)
Format: Article
Language:English
Published: Elsevier B.V., 2017-03-27T20:03:34Z.
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