A distant trophoblast-specific enhancer controls HLA-G expression at the maternal-fetal interface

A distant trophoblast-specific enhancer controls HLA-G expression at the maternal-fetal interface

HLA-G, a nonclassical HLA molecule uniquely expressed in the placenta, is a central component of fetus-induced immune tolerance during pregnancy. The tissue-specific expression of HLA-G, however, remains poorly understood. Here, systematic interrogation of the HLA-G locus using massively parallel re...

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Bibliographic Details
Main Authors: Ferreira, Leonardo M. R. (Author), Meissner, Torsten B. (Author), Mikkelsen, Tarjei S. (Author), Mallard, William (Author), O'Donnell, Charles W. (Author), Tilburgs, Tamara (Author), Gomes, Hannah A. B. (Author), Camahort, Raymond (Author), Sherwood, Richard I. (Author), Rinn, John L. (Author), Cowan, Chad A. (Author), Strominger, Jack L. (Author), Gifford, David K (Contributor)
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2017-04-07T20:16:17Z.
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