Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer

Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer

The National Institute on Aging Interventions Testing Program (ITP) evaluates agents hypothesized to increase healthy lifespan in genetically heterogeneous mice. Each compound is tested in parallel at three sites, and all results are published. We report the effects of lifelong treatment of mice wit...

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Main Authors: Strong, Randy (Author), Miller, Richard A. (Author), Antebi, Adam (Author), Astle, Clinton M. (Author), Bogue, Molly (Author), Denzel, Martin S. (Author), Fernandez, Elizabeth (Author), Flurkey, Kevin (Author), Hamilton, Karyn L. (Author), Lamming, Dudley W. (Author), Javors, Martin A. (Author), de Magalhães, João Pedro (Author), Martinez, Paul Anthony (Author), McCord, Joe M. (Author), Miller, Benjamin F. (Author), Müller, Michael (Author), Nelson, James F. (Author), Ndukum, Juliet (Author), Rainger, G. Ed (Author), Richardson, Arlan (Author), Salmon, Adam B. (Author), Simpkins, James W. (Author), Steegenga, Wilma T. (Author), Nadon, Nancy L. (Author), Harrison, David E. (Author), Sabatini, David (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor)
Format: Article
Language:English
Published: Wiley Blackwell, 2017-04-14T19:33:41Z.
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