Liposomal vaccines incorporating molecular adjuvants and intrastructural T-cell help promote the immunogenicity of HIV membrane-proximal external region peptides

An HIV vaccine capable of inducing high and durable levels of broadly neutralizing antibodies has thus far proven elusive. A promising antigen is the membrane-proximal external region (MPER) from gp41, a segment of the viral envelope recognized by a number of broadly neutralizing antibodies. Though...

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Bibliographic Details
Main Authors: Kim, Mikyung (Author), Reinherz, Ellis L. (Author), Abraham, Wuhbet (Contributor), Hanson, Melissa Catherine (Contributor), Liu, Haipeng (Contributor), Szeto, Gregory (Contributor), Irvine, Darrell J (Contributor), Chen, Stephanie H. (Contributor), Crespo, Monica P. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Materials Science and Engineering (Contributor), Ragon Institute of MGH, MIT and Harvard (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Crespo, Monica P (Contributor)
Format: Article
Language:English
Published: Elsevier, 2017-04-14T20:09:39Z.
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