CD4+ T cell-dependent and CD4+ T cell-independent cytokine-chemokine network changes in the immune responses of HIV-infected individuals

A vital defect in the immune systems of HIV-infected individuals is the loss of CD4⁺ T cells, resulting in impaired immune responses. We hypothesized that there were CD4⁺ T cell-dependent and CD4⁺ T cell-independent alterations in the immune responses of HIV-1⁺ individuals. To test this, we analyzed...

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Bibliographic Details
Main Authors: Lauffenburger, Douglas A (Contributor), Szeto, Gregory (Contributor), Alter, Galit (Contributor), Irvine, Darrell J (Contributor), Arnold, Kelly B. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Ragon Institute of MGH, MIT and Harvard (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Arnold, Kelly Benedict (Contributor)
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS), 2017-04-18T20:46:22Z.
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