Functional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosis

Functional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosis

Myelin-reactive T cells have been identified in patients with multiple sclerosis (MS) and healthy subjects with comparable frequencies, but the contribution of these autoreactive T cells to disease pathology remains unknown. A total of 13,324 T cell libraries generated from blood of 23 patients and...

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Main Authors: Cao, Y. (Author), Raddassi, K. (Author), Nepom, G. T. (Author), Kwok, W. W. (Author), Goods, Brittany A. (Contributor), Love, John C (Contributor), Hafler, David A. (Author)
Other Authors: Broad Institute of MIT and Harvard (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Hafler, David A (Contributor)
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS), 2017-05-31T13:58:02Z.
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