A novel role for transcription-coupled nucleotide excision repair for the in vivo repair of 3, N[superscript4]-ethenocytosine
Etheno (ε) DNA base adducts are highly mutagenic lesions produced endogenously via reactions with lipid peroxidation (LPO) products. Cancer-promoting conditions, such as inflammation, can induce persistent oxidative stress and increased LPO, resulting in the accumulation of ε-adducts in different ti...
Main Authors: | , , , , , |
---|---|
Other Authors: | , , |
Format: | Article |
Language: | English |
Published: |
Oxford University Press,
2017-06-21T16:06:33Z.
|
Subjects: | |
Online Access: | Get fulltext |