A Population Dynamics Model for Clonal Diversity in a Germinal Center

A Population Dynamics Model for Clonal Diversity in a Germinal Center

Germinal centers (GCs) are micro-domains where B cells mature to develop high affinity antibodies. Inside a GC, B cells compete for antigen and T cell help, and the successful ones continue to evolve. New experimental results suggest that, under identical conditions, a wide spectrum of clonal divers...

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Bibliographic Details
Main Authors: Mesin, Luka (Author), Victora, Gabriel D. (Author), Amitai, Assaf (Contributor), Kardar, Mehran (Contributor), Chakraborty, Arup K (Contributor)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor), Massachusetts Institute of Technology. Department of Physics (Contributor)
Format: Article
Language:English
Published: Frontiers Research Foundation, 2017-12-29T20:25:19Z.
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