SYK kinase mediates brown fat differentiation and activation

SYK kinase mediates brown fat differentiation and activation

Brown adipose tissue (BAT) metabolism influences glucose homeostasis and metabolic health in mice and humans. Sympathetic stimulation of β-adrenergic receptors in response to cold induces proliferation, differentiation, and UCP1 expression in pre-adipocytes and mature brown adipocytes. Here we show...

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Main Authors: Knoll, Marko (Author), Winther, Sally (Author), Natarajan, Anirudh (Author), Yang, Huan (Author), Jiang, Mengxi (Author), Thiru, Prathapan (Author), Shahsafaei, Aliakbar (Author), Chavarria, Tony E. (Author), Lamming, Dudley W. (Author), Sun, Lei (Author), Hansen, Jacob B. (Author), Lodish, Harvey F (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2018-02-13T14:39:49Z.
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