A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress

A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress

Cisplatin and its platinum analogs, carboplatin and oxaliplatin, are some of the most widely used cancer chemotherapeutics. Although cisplatin and carboplatin are used primarily in germ cell, breast and lung malignancies, oxaliplatin is instead used almost exclusively to treat colorectal and other g...

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Main Authors: Murai, Junko (Author), Pommier, Yves (Author), Hemann, Michael T (Author), Bruno, Peter Michael (Contributor), Liu, Yunpeng (Contributor), Park, Ga Young (Contributor), Koch, Catherine E. (Contributor), Lippard, Stephen J. (Contributor), Hemann, Michael (Contributor), Eisen, Timothy Jonas (Author), Pritchard, Justin R. (Author)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Eisen, Timothy (Contributor), Pritchard, Justin Robert (Contributor)
Format: Article
Language:English
Published: Springer Nature, 2018-06-25T14:14:29Z.
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