A Phase Separation Model for Transcriptional Control

A Phase Separation Model for Transcriptional Control

Phase-separated multi-molecular assemblies provide a general regulatory mechanism to compartmentalize biochemical reactions within cells. We propose that a phase separation model explains established and recently described features of transcriptional control. These features include the formation of...

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Bibliographic Details
Main Authors: Hnisz, Denes (Author), Young, Richard A. (Contributor), Chakraborty, Arup K. (Contributor), Sharp, Phillip A. (Contributor), Shrinivas, Krishna,Ph. D.Massachusetts Institute of Technology (Author)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor), Massachusetts Institute of Technology. Department of Physics (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Shrinivas, Krishna (Contributor)
Format: Article
Language:English
Published: Elsevier, 2018-07-09T17:57:51Z.
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