Transcriptional Dysregulation of MYC Reveals Common Enhancer-Docking Mechanism
Transcriptional dysregulation of the MYC oncogene is among the most frequent events in aggressive tumor cells, and this is generally accomplished by acquisition of a super-enhancer somewhere within the 2.8 Mb TAD where MYC resides. We find that these diverse cancer-specific super-enhancers, differin...
Main Authors: | , , , , , , , |
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Other Authors: | , |
Format: | Article |
Language: | English |
Published: |
Elsevier,
2018-07-23T16:50:12Z.
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Subjects: | |
Online Access: | Get fulltext |