Transcriptional Addiction in Cancer

Cancer arises from genetic alterations that invariably lead to dysregulated transcriptional programs. These dysregulated programs can cause cancer cells to become highly dependent on certain regulators of gene expression. Here, we discuss how transcriptional control is disrupted by genetic alteratio...

Full description

Bibliographic Details
Main Authors: Bradner, James E. (Author), Hnisz, Denes (Author), Young, Richard A. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Richard Young (Contributor), Young, Richard A (Contributor)
Format: Article
Language:English
Published: Elsevier, 2018-08-06T18:17:13Z.
Subjects:
Online Access:Get fulltext