A liver microphysiological system of tumor cell dormancy and inflammatory responsiveness is affected by scaffold properties

A liver microphysiological system of tumor cell dormancy and inflammatory responsiveness is affected by scaffold properties

Distant metastasis is the major cause of breast cancer-related mortality, commonly emerging clinically after 5 or more years of seeming 'cure'of the primary tumor, indicating a quiescent dormancy. The lack of relevant accessible model systems for metastasis that recreate this latent stage...

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Main Authors: Wheeler, S. E. (Author), Stolz, D. B. (Author), Venkataramanan, R. (Author), Wells, A. (Author), Shepard, Nieman J. (Author), Clark, Abigail M (Contributor), Young, Carissa L. (Contributor), Stockdale, Linda (Contributor), Zhao, Weian (Contributor), Lauffenburger, Douglas A (Contributor), Griffith, Linda G (Contributor)
Other Authors: Massachusetts Institute of Technology. Biotechnology Process Engineering Center (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor)
Format: Article
Language:English
Published: Royal Society of Chemistry (RSC), 2018-09-04T13:24:41Z.
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