ADAM10 Sheddase Activity is a Potential Lung-Cancer Biomarker

ADAM10 Sheddase Activity is a Potential Lung-Cancer Biomarker

Background: Increases in expression of ADAM10 and ADAM17 genes and proteins are inconsistently found in cancer lesions, and are not validated as clinically useful biomarkers. The enzyme-specific proteolytic activities, which are solely mediated by the active mature enzymes, directly reflect enzyme c...

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Main Authors: Yoneyama, Toshie (Author), Gorry, Michael (Author), Sobo-Vujanovic, Andrea (Author), Lin, Yan (Author), Vujanovic, Lazar (Author), Gaither-Davis, Autumn (Author), Moss, Marcia L. (Author), Stabile, Laura P. (Author), Herman, James (Author), Vujanovic, Nikola L. (Author), Miller, Miles Aaron (Contributor), Griffith, Linda G (Contributor), Lauffenburger, Douglas A (Contributor)
Other Authors: Massachusetts Institute of Technology. Biotechnology Process Engineering Center (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor)
Format: Article
Language:English
Published: Ivyspring International Publisher, 2018-09-05T16:13:56Z.
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