Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV

Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV

Antibodies are the primary correlate of protection for most licensed vaccines; however, their mechanisms of protection vary, ranging from physical blockade to clearance via the recruitment of innate immunity. Here, we uncover striking functional diversity in vaccine-induced antibodies associated wit...

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Main Authors: Ackerman, Margaret E. (Author), Pittala, Srivamshi (Author), Broge, Thomas (Author), Linde, Caitlyn (Author), Suscovich, Todd J. (Author), Brown, Eric P. (Author), Bradley, Todd (Author), Natarajan, Harini (Author), Lin, Shu (Author), Sassic, Jessica K. (Author), O'Keefe, Sean (Author), Mehta, Nickita (Author), Goodman, Derrick (Author), Sips, Magdalena (Author), Weiner, Joshua A. (Author), Tomaras, Georgia D. (Author), Haynes, Barton F. (Author), Bailey-Kellogg, Chris (Author), Roederer, Mario (Author), Alter, Galit (Author), Lauffenburger, Douglas A (Contributor), Das, Jishnu (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Ragon Institute of MGH, MIT and Harvard (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2018-10-09T15:02:39Z.
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