Fitness landscape of the human immunodeficiency virus envelope protein that is targeted by antibodies

HIV is a highly mutable virus, and over 30 years after its discovery, a vaccine or cure is still not available. The isolation of broadly neutralizing antibodies (bnAbs) from HIV-infected patients has led to renewed hope for a prophylactic vaccine capable of combating the scourge of HIV. A major chal...

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Bibliographic Details
Main Authors: Louie, Raymond H. Y. (Author), Kaczorowski, Kevin John (Contributor), Barton, John P (Contributor), Chakraborty, Arup K (Contributor), McKay, Matthew (Contributor)
Other Authors: Institute for Medical Engineering and Science (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor), Massachusetts Institute of Technology. Department of Physics (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2018-10-12T17:44:11Z.
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