Epigenetic Modulation Using Small Molecules - Targeting Histone Acetyltransferases in Disease

Histone acetyltransferases (HATs) are epigenetic drivers that catalyze the acetyl transfer from acetyl-CoA to lysines of both histone and non-histone substrates and thereby induce transcription either by chromatin remodeling or direct transcription factor activation. Histone deacetylases (HDACs) con...

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Bibliographic Details
Main Authors: Richters, Andre (Contributor), Koehler, Angela Nicole (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Koehler, Angela N (Contributor)
Format: Article
Language:English
Published: Bentham Science, 2018-11-05T19:15:35Z.
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