CRISPR-based genomic tools for the manipulation of genetically intractable microorganisms

CRISPR-based genomic tools for the manipulation of genetically intractable microorganisms

Genetic manipulation of microorganisms has been crucial in understanding their biology, yet for many microbial species, robust tools for comprehensive genetic analysis were lacking until the advent of CRISPR-Cas-based gene editing techniques. In this Progress article, we discuss advances in CRISPR-b...

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Bibliographic Details
Main Authors: Chavez, Alejandro (Author), Collins, James J. (Contributor), Shapiro, Rebecca (Author)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Synthetic Biology Center (Contributor), Collins, James J (Contributor), Shapiro, Rebecca Sara (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2018-12-07T18:05:24Z.
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