In Vitro Culture, Drug Sensitivity, and Transcriptome of Plasmodium Vivax Hypnozoites

In Vitro Culture, Drug Sensitivity, and Transcriptome of Plasmodium Vivax Hypnozoites

The unique relapsing nature of Plasmodium vivax infection is a major barrier to malaria eradication. Upon infection, dormant liver-stage forms, hypnozoites, linger for weeks to months and then relapse to cause recurrent blood-stage infection. Very little is known about hypnozoite biology; definitive...

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Main Authors: Gural, Nil (Author), Mancio Silva, Liliana (Author), Miller, Alex B (Author), Galstian, Ani (Author), Butty, Vincent L (Author), Levine, Stuart S (Author), Patrapuvich, Rapatbhorn (Author), Desai, Salil P (Author), Mikolajczak, Sebastian A (Author), Kappe, Stefan H. I. (Author), Fleming, Heather (Author), March-Riera, Sandra (Author), Sattabongkot, Jetsumon (Author), Bhatia, Sangeeta N (Author)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Elsevier BV, 2019-05-29T19:47:40Z.
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