Assessment of Drug-Induced Toxicity Biomarkers in the Brain Microphysiological System (MPS) Using Targeted and Untargeted Molecular Profiling

Early assessment of adverse drug effects in humans is critical to avoid long-lasting harm. However, current approaches for early detection of adverse effects still lack predictive and organ-specific biomarkers to evaluate undesired responses in humans. Microphysiological systems (MPSs) are in vitro...

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Bibliographic Details
Main Authors: Mina, Sara G. (Author), Alaybeyoglu, Begum (Author), Murphy, William L. (Author), Thomson, James A. (Author), Stokes, Cynthia L. (Author), Cirit, Murat (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: Frontiers Media SA, 2020-04-02T15:18:20Z.
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