Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis
Genome-wide association studies (GWAS) have revealed risk alleles for ulcerative colitis (UC). To understand their cell type specificities and pathways of action, we generate an atlas of 366,650 cells from the colon mucosa of 18 UC patients and 12 healthy individuals, revealing 51 epithelial, stroma...
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Bibliographic Details
| Main Authors: |
Ordovas-Montanes, Jose Manuel
(Author),
Graham, Daniel B.
(Author),
Shalek, Alexander K
(Author),
Xavier, Ramnik Joseph
(Author),
Regev, Aviv
(Author) |
|---|
| Other Authors: |
Massachusetts Institute of Technology. Department of Chemistry
(Contributor),
Massachusetts Institute of Technology. Institute for Medical Engineering & Science
(Contributor),
Ragon Institute of MGH, MIT and Harvard
(Contributor),
Massachusetts Institute of Technology. Center for Microbiome Informatics and Therapeutics
(Contributor),
Massachusetts Institute of Technology. Department of Biology
(Contributor),
Koch Institute for Integrative Cancer Research at MIT
(Contributor) |
|---|
| Format: | Article
|
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| Language: | English |
|---|
| Published: |
Elsevier BV,
2020-08-26T17:28:41Z.
|
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| Subjects: | |
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| Online Access: | Get fulltext
|
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