Wnt Signaling Separates the Progenitor and Endocrine Compartments during Pancreas Development

Wnt Signaling Separates the Progenitor and Endocrine Compartments during Pancreas Development

In vitro differentiation of pluripotent cells into β cells is a promising alternative to cadaveric-islet transplantation as a cure for type 1 diabetes (T1D). During the directed differentiation of human embryonic stem cells (hESCS) by exogenous factors, numerous genes that affect the differentiation...

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Main Authors: Sharon, Nadav (Author), Vanderhooft, Jordan (Author), Straubhaar, Juerg (Author), Mueller, Jonas Weylin (Author), Chawla, Raghav (Author), Zhou, Quan (Author), Engquist, Elise N. (Author), Trapnell, Cole (Author), Gifford, David K (Author), Melton, Douglas A. (Author)
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor)
Format: Article
Language:English
Published: Elsevier BV, 2020-12-23T20:50:09Z.
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